Three Reasons Why You Want Beta Alanine
By
David Barr

Sports supplements suck. It seems like 98 percent of claims are pure bullshit
and the rest are about creatine. To be fair, it looks as though there’s a strong
case for using carnitine tartrate for growth and strength (1) as well as neural
recovery (2). However, there’s another supplement that you may be interested in.
Beta alanine (BA) is most often used by non-strength athletes for its ability
to buffer acid and keep the muscle working harder for longer. This not only
results directly in increased performance but also the magnitude of the training
stimulus. The reason that strength athletes may be interested is a little more
nebulous. Basically, it concerns the particular attributes that aren’t
immediately obvious when looking at this amino acid product.
Note: For a look at using protein for optimal recovery, see the widely used
article on “Protein
Pulse Feeding.”
Neural recovery
I’m usually the first one to jump on the patently lazy generalization of the
word “recovery,” but this is exactly where BA’s ill-defined nature comes in. The
thing is that with the effects of BA we’re potentially enhancing neural recovery
as well as a larger scale endocrine-based recovery. This single multi-pronged
effect is quite impressive considering how difficult it is to actually promote
recovery, especially with an athletic supplement.
If you’ve read the information about carnitine and its theoretical basis for
neural recovery, you’ll already know that our nervous system is the first
physiological effector to be stimulated and the last to recover. Other than
simple rest, there are few ways of accelerating neural recovery.
One theory supporting the use of BA for neural recovery is the protective
effect it ultimately confers on something called the sodium pump. Without
getting into detail, it is this molecular “pump” that is responsible for the
transmission of every signal that flows through our nerve cells. This includes
everything from reading these very words to muscle contraction during a lift.
Unfortunately, the sodium pump is quite susceptible to oxidative damage (6), and
this damage is thought to impair performance (7).
Fortunately, BA converts to a substance known as carnosine (see the
post-cycle therapy section for more information), which protects the pump from
oxidative damage (4). Through this prophylactic effect, BA can mitigate a
superfluous stressor on our nerve cells, thereby ultimately increasing the rate
of recovery.
Bonus: Carnosine even has the ability to stimulate the activity of the sodium
pump, which has further implications for improved performance (3).
General/endocrine recovery
A much broader mechanism through which BA can assist with recovery pertains
to its neurotransmitter-like abilities. Before we get into that though, we need
to recognize an important, rarely discussed point—recovery begins the second the
training session is over.
I’m sure it would be simple enough to make a case for an earlier start of
recovery, but the key idea remains. When we no longer have any need for whole
body excitation, we need to relax. Stated differently, we need to turn off our
sympathetic nervous system and turn on our parasympathetic.
Any superfluous excitability only serves to further stress the endocrine
system and likely the nervous system as well as delay recovery (this is what
makes stimulant use a double-edged sword). By consuming BA post-workout, we
stimulate receptors for a neurotransmitter called GABA, which is great at
slowing down the nervous system and allowing us to recover (5).
This transient GABA-ergic effect results in not only an inhibitory effect on
the nervous system, but this should facilitate a whole body relaxation. The next
major affected system of interest is the endocrine system, the over-stimulation
of which is often implicated in overtraining. Although there are no direct data
supporting the hypothesis that BA could retard or even prevent overtraining, the
possibility remains…“exciting.”
Post-cycle therapy
Another benefit of BA is that it is of tremendous help during post-androgen
therapy. The reasoning for this requires a couple of lines about BA’s mechanism
of action, but it’s not something we need to get bogged down with.
Basically, BA works by combining with the amino acid, histidine, to form a
compound called carnosine (as briefly discussed above). Although there are
positive attributes to BA supplementation, all of the (non-GABA based) positive
effects are ultimately a result of increasing muscle carnosine concentration.
This is important because one of the mechanisms of androgen action is an
increase in muscle carnosine (8). Conversely, it should be no surprise that
following androgen treatment, muscle carnosine levels return to normal and
patients experience a decrease in performance. By using BA to maintain muscle
carnosine levels, there is no post-therapy reduction to normalcy, and some level
of elevated performance can be maintained.
BA is a versatile supplement that has ergogenic potential across numerous
performance goals. Although neural recovery is important for all, it is likely
no more important anywhere than in strength sports. Given the paucity of
efficacious supplements to support these goals, BA has the potential to make a
major impact in your performance.
Until next time, raise your expectations. Raise the Barr!
References
- Barr D (2008) Optimizing Muscle Strength and Recovery with CLT.
EliteFTS.
- Barr D (2008) Neural Performance and Recovery with Carnitine-L-Tartrate.
EliteFTS.
- Boldyrev AA, Stvolinsky SL, Tyulina OV, Koshelev VB, Hori N, Carpenter
DO (1997) Biochemical and physiological evidence that carnosine is an
endogenous neuroprotector against free radicals. Cell Mol Neurobiol
17(2):259–71.
- Boldyrev A, Bulygina E, Leinsoo T, Petrushanko I, Tsubone S, Abe H
(2004) Protection of neuronal cells against reactive oxygen species by
carnosine and related compounds. Comp Biochem Physiol B Biochem Mol Biol
137(1):81–8.
- Enna SJ, Snyder SH (1975) Properties of gamma-aminobutyric acid (GABA)
receptor binding in rat brain synaptic membrane fractions. Brain Res
100(1):81–97.
- Fowles JR, Green HJ, Tupling R, O’Brien S, Roy BD (2002) Human
neuromuscular fatigue is associated with altered Na+-K+-ATPase activity
following isometric exercise. J Appl Physiol 92(4):1585–93.
- Green HJ (1997) Mechanisms of muscle fatigue in intense exercise. J
Sports Sci 15(3):247–56.
- Penafiel R, Ruzafa C, Monserrat F, Cremades A (2004) Gender-related
differences in carnosine, anserine and lysine content of murine skeletal
muscle. Amino Acids 26(1):53–8.
David Barr is widely recognized as an industry innovator, most recently
for his work on developing the Anabolic Index. As a strength coach and
scientist, he brings a unique perspective to the areas of diet, supplementation,
and training. His research experience includes work for NASA at the Johnson
Space Center as well as studying the effects of protein on muscle growth. David
holds certifications with the NSCA and USA Track and Field. He can be contacted
through his website at
http://www.RaiseTheBarr.net.
Elite Fitness Systems strives to be a recognized leader in the strength
training industry by providing the highest quality strength training products
and services while providing the highest level of customer service in the
industry. For the best training equipment, information, and accessories, visit
us at www.EliteFTS.com.