Research using brain imaging technology has revealed a brain response pattern in children that might represent a step along the path to childhood obesity. The study, conducted by Nicole Fearnbach, a graduate student in Penn State University's Department of Nutritional Sciences, scanned children's brain activity while they viewed pictures of high- and low-calorie foods, and found that both lean body mass and body fat are linked to how kids' brains respond to food.

Fearnbach and her colleagues discovered the neural activation in this brain area differed in children of different weight groups. Children with greater lean body weight had more powerful brain response in the substantia nigra when looking at high-calorie foods compared to children with lower lean body weight. The study also found that children with higher body fat had lower activity in this same brain area when they saw pictures of healthier, low-calorie foods like fruits, vegetables, and grilled chicken.

"We think that kids with more lean body weight might have a greater reward response to higher calorie foods, in part because they have greater energy needs compared to children with less lean body weight. Lean body weight largely determines how many calories we burn each day through our resting metabolic rate. Bigger kids burn more calories, and our results show that their brains respond differently to foods," explained Fearnbach.

"Interestingly, we also found that children with more body fat had a reduced brain response to lower calorie foods, which tend to be the healthier options," Fearnbach added. "It might be that kids with higher body fat find those healthier foods to be less rewarding. But we don't know yet whether having more body fat is a cause or a consequence of these brain responses."